Found 3 hits for monomerid = 50326612 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50326612
(2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylben...)Show SMILES CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3C)cc12 Show InChI InChI=1S/C21H20BrN5/c1-13-6-3-4-7-14(13)10-16-12-18-19(24-16)25-21(23)26-20(18)27(2)17-9-5-8-15(22)11-17/h3-9,11-12H,10H2,1-2H3,(H3,23,24,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description
Inhibition of EGFR expressed in human A431 cells |
Bioorg Med Chem 18: 5261-73 (2010)
Article DOI: 10.1016/j.bmc.2010.05.049
BindingDB Entry DOI: 10.7270/Q29Z95W6 |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50326612
(2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylben...)Show SMILES CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3C)cc12 Show InChI InChI=1S/C21H20BrN5/c1-13-6-3-4-7-14(13)10-16-12-18-19(24-16)25-21(23)26-20(18)27(2)17-9-5-8-15(22)11-17/h3-9,11-12H,10H2,1-2H3,(H3,23,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta expressed in human A431 cells |
Bioorg Med Chem 18: 5261-73 (2010)
Article DOI: 10.1016/j.bmc.2010.05.049
BindingDB Entry DOI: 10.7270/Q29Z95W6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50326612
(2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylben...)Show SMILES CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3C)cc12 Show InChI InChI=1S/C21H20BrN5/c1-13-6-3-4-7-14(13)10-16-12-18-19(24-16)25-21(23)26-20(18)27(2)17-9-5-8-15(22)11-17/h3-9,11-12H,10H2,1-2H3,(H3,23,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 expressed in human A431 cells |
Bioorg Med Chem 18: 5261-73 (2010)
Article DOI: 10.1016/j.bmc.2010.05.049
BindingDB Entry DOI: 10.7270/Q29Z95W6 |
More data for this
Ligand-Target Pair | |
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