null

SMILES: Cc1ccccc1Cc1cc2c(Nc3cccc(Br)c3)nc(N)nc2n1C

InChI Key: InChIKey=QUYCCARCAMJDBA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50326613 (2-Amino-4-(m-bromoanilino)-6-(2-methylbenzyl)-7-me...) Show SMILES Cc1ccccc1Cc1cc2c(Nc3cccc(Br)c3)nc(N)nc2n1C Show InChI InChI=1S/C21H20BrN5/c1-13-6-3-4-7-14(13)10-17-12-18-19(24-16-9-5-8-15(22)11-16)25-21(23)26-20(18)27(17)2/h3-9,11-12H,10H2,1-2H3,(H3,23,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGFR expressed in human A431 cells				Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50326613 (2-Amino-4-(m-bromoanilino)-6-(2-methylbenzyl)-7-me...) Show SMILES Cc1ccccc1Cc1cc2c(Nc3cccc(Br)c3)nc(N)nc2n1C Show InChI InChI=1S/C21H20BrN5/c1-13-6-3-4-7-14(13)10-17-12-18-19(24-16-9-5-8-15(22)11-16)25-21(23)26-20(18)27(17)2/h3-9,11-12H,10H2,1-2H3,(H3,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta expressed in human A431 cells				Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50326613 (2-Amino-4-(m-bromoanilino)-6-(2-methylbenzyl)-7-me...) Show SMILES Cc1ccccc1Cc1cc2c(Nc3cccc(Br)c3)nc(N)nc2n1C Show InChI InChI=1S/C21H20BrN5/c1-13-6-3-4-7-14(13)10-17-12-18-19(24-16-9-5-8-15(22)11-16)25-21(23)26-20(18)27(17)2/h3-9,11-12H,10H2,1-2H3,(H3,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 expressed in human A431 cells				Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6
					More data for this Ligand-Target Pair