BDBM50327011 (S)-4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-(1-phenylethyl)pyrrolo[1,2-f][1,2,4]triazine-6-carboxamide::CHEMBL1254661

SMILES: C[C@H](NC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(=O)NC3CC3)c2c1C)c1ccccc1

InChI Key: InChIKey=IEGNGCQIWONZRP-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327011 ((S)-4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamin...) Show SMILES C[C@H](NC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(=O)NC3CC3)c2c1C)c1ccccc1 |r| Show InChI InChI=1S/C27H28N6O2/c1-16-9-10-20(26(34)31-21-11-12-21)13-23(16)32-25-24-17(2)22(14-33(24)29-15-28-25)27(35)30-18(3)19-7-5-4-6-8-19/h4-10,13-15,18,21H,11-12H2,1-3H3,(H,30,35)(H,31,34)(H,28,29,32)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 mins				J Med Chem 53: 6629-39 (2010) Article DOI: 10.1021/jm100540x BindingDB Entry DOI: 10.7270/Q2JM29T1
					More data for this Ligand-Target Pair