BDBM50327052 4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]-Nphenylbenzamide::CHEMBL1255094

SMILES: Cn1ccc2ncnc(Oc3ccc(cc3)C(=O)Nc3ccccc3)c12

InChI Key: InChIKey=CESRDTYIWAIHRI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50327052 (4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]-...) Show SMILES Cn1ccc2ncnc(Oc3ccc(cc3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C20H16N4O2/c1-24-12-11-17-18(24)20(22-13-21-17)26-16-9-7-14(8-10-16)19(25)23-15-5-3-2-4-6-15/h2-13H,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem 18: 7260-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.017 BindingDB Entry DOI: 10.7270/Q2NC61DC
					More data for this Ligand-Target Pair