BDBM50327057 1-Methyl-3-{4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-oxy]phenyl}urea::CHEMBL1254590

SMILES: CNC(=O)Nc1ccc(Oc2ncnc3ccn(C)c23)cc1

InChI Key: InChIKey=DQLNSXWMOVNYKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50327057 (1-Methyl-3-{4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidi...) Show SMILES CNC(=O)Nc1ccc(Oc2ncnc3ccn(C)c23)cc1 Show InChI InChI=1S/C15H15N5O2/c1-16-15(21)19-10-3-5-11(6-4-10)22-14-13-12(17-9-18-14)7-8-20(13)2/h3-9H,1-2H3,(H2,16,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem 18: 7260-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.017 BindingDB Entry DOI: 10.7270/Q2NC61DC
					More data for this Ligand-Target Pair