BDBM50327065 1-(3-Methylphenyl)-3-{4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea::CHEMBL1254923
SMILES: Cc1cccc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2)c1
InChI Key: InChIKey=FAICIPSJBXCWEZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50327065 (1-(3-Methylphenyl)-3-{4-[(5-methyl-5H-pyrrolo[3,2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human VEGFR2 | Bioorg Med Chem 18: 7260-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.017 BindingDB Entry DOI: 10.7270/Q2NC61DC | |||||||||||
More data for this Ligand-Target Pair |