BDBM50327067 1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)amino]-phenyl}-3-phenylurea::CHEMBL1254003

SMILES: Cn1ccc2ncnc(Nc3ccc(NC(=O)Nc4ccccc4)cc3)c12

InChI Key: InChIKey=WVMBSZUGHXTYFF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50327067 (1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)am...) Show SMILES Cn1ccc2ncnc(Nc3ccc(NC(=O)Nc4ccccc4)cc3)c12 Show InChI InChI=1S/C20H18N6O/c1-26-12-11-17-18(26)19(22-13-21-17)23-15-7-9-16(10-8-15)25-20(27)24-14-5-3-2-4-6-14/h2-13H,1H3,(H,21,22,23)(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem 18: 7260-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.017 BindingDB Entry DOI: 10.7270/Q2NC61DC
					More data for this Ligand-Target Pair