BDBM50327497 8-(1-(cyclopropylmethyl)piperidin-4-yloxy)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-one::CHEMBL1255600

SMILES: O=C1NCCn2c1cc1cc(OC3CCN(CC4CC4)CC3)ccc21

InChI Key: InChIKey=HBHVWXDHDUQMRV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327497 (8-(1-(cyclopropylmethyl)piperidin-4-yloxy)-3,4-dih...) Show SMILES O=C1NCCn2c1cc1cc(OC3CCN(CC4CC4)CC3)ccc21 Show InChI InChI=1S/C20H25N3O2/c24-20-19-12-15-11-17(3-4-18(15)23(19)10-7-21-20)25-16-5-8-22(9-6-16)13-14-1-2-14/h3-4,11-12,14,16H,1-2,5-10,13H2,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-RAMH from human histamine H3 receptor				Bioorg Med Chem Lett 20: 5713-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.009 BindingDB Entry DOI: 10.7270/Q2571C7N
					More data for this Ligand-Target Pair