BDBM50327498 6-(1-isopropylpiperidin-4-yloxy)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one::CHEMBL1258753

SMILES: CC(C)N1CCC(CC1)Oc1ccc2[nH]c3c(CCNC3=O)c2c1

InChI Key: InChIKey=YIMUYPNUNRVCQR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327498 (6-(1-isopropylpiperidin-4-yloxy)-2,3,4,9-tetrahydr...) Show SMILES CC(C)N1CCC(CC1)Oc1ccc2[nH]c3c(CCNC3=O)c2c1 Show InChI InChI=1S/C19H25N3O2/c1-12(2)22-9-6-13(7-10-22)24-14-3-4-17-16(11-14)15-5-8-20-19(23)18(15)21-17/h3-4,11-13,21H,5-10H2,1-2H3,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-RAMH from human histamine H3 receptor				Bioorg Med Chem Lett 20: 5713-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.009 BindingDB Entry DOI: 10.7270/Q2571C7N
					More data for this Ligand-Target Pair