BDBM50327499 2-(5-(1H-pyrazol-4-yl)pyridin-3-yl)-1-fluoroethane-1,1-diyldiphosphonic acid::CHEMBL1258422

SMILES: OP(O)(=O)C(F)(Cc1cncc(c1)-c1cn[nH]c1)P(O)(O)=O

InChI Key: InChIKey=AOQKAONFTODMIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50327499 (2-(5-(1H-pyrazol-4-yl)pyridin-3-yl)-1-fluoroethane...) Show SMILES OP(O)(=O)C(F)(Cc1cncc(c1)-c1cn[nH]c1)P(O)(O)=O Show InChI InChI=1S/C10H12FN3O6P2/c11-10(21(15,16)17,22(18,19)20)2-7-1-8(4-12-3-7)9-5-13-14-6-9/h1,3-6H,2H2,(H,13,14)(H2,15,16,17)(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli				Bioorg Med Chem Lett 20: 5781-6 (2010) Article DOI: 10.1016/j.bmcl.2010.07.133 BindingDB Entry DOI: 10.7270/Q21G0MGG
					More data for this Ligand-Target Pair