BindingDB PrimarySearch

BDBM50327861 (1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate::CHEMBL1258452

SMILES: CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1

InChI Key: InChIKey=DZZIAERGLDKTBT-UHFFFAOYSA-N

Data: 43 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50327861
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
HTR4 (GUINEA PIG)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.738	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranes				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4 receptor expressed in HEK293 cells				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat sigma 1 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	989	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human adrenergic Alpha-2C receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M3 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat dopamine D4 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
HRH3 (GUINEA PIG)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to guinea pig histamine H3 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M4 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT2B receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT3 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M5 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human adrenergic Alpha-1B receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat adrenergic beta-1 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT1D receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat dopamine D3 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human SERT				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human adrenergic alpha1A receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human adrenergic Alpha-1D receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human adrenergic alpha2A receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT1E receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat adrenergic beta2 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adrenergic receptor beta (Rattus norvegicus)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat adrenergic beta3 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human DAT				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat dopamine D1 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to rat dopamine D2 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT1B receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human dopamine D5 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to guinea pig histamine H1 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to guinea pig histamine H2 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT1A receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H4 receptor (GUINEA PIG)	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to guinea pig histamine H4 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human kappa opioid receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M1 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human mu opioid receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M2 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human delta opioid receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human adrenergic alpha2B receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human NET				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT7 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT6 receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT2C receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT2A receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50327861 ((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...) Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 Show InChI	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human 5-HT5A receptor				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair