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BDBM50327864 (1-Butylpiperidin-4-yl)methyl 4-Amino-3-(fluoromethoxy)-benzoate::CHEMBL1258672

SMILES: CCCCN1CCC(COC(=O)c2ccc(N)c(OCF)c2)CC1

InChI Key: InChIKey=BVDPGNIRFHUQHL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327864   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HTR4


(GUINEA PIG)
BDBM50327864
PNG
((1-Butylpiperidin-4-yl)methyl 4-Amino-3-(fluoromet...)
Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OCF)c2)CC1
Show InChI InChI=1S/C18H27FN2O3/c1-2-3-8-21-9-6-14(7-10-21)12-23-18(22)15-4-5-16(20)17(11-15)24-13-19/h4-5,11,14H,2-3,6-10,12-13,20H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.334n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranes


J Med Chem 53: 7035-47 (2010)


Article DOI: 10.1021/jm100668r
BindingDB Entry DOI: 10.7270/Q2BR8SD7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4)


(Homo sapiens (Human))
BDBM50327864
PNG
((1-Butylpiperidin-4-yl)methyl 4-Amino-3-(fluoromet...)
Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OCF)c2)CC1
Show InChI InChI=1S/C18H27FN2O3/c1-2-3-8-21-9-6-14(7-10-21)12-23-18(22)15-4-5-16(20)17(11-15)24-13-19/h4-5,11,14H,2-3,6-10,12-13,20H2,1H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
17n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4 receptor expressed in HEK293 cells


J Med Chem 53: 7035-47 (2010)


Article DOI: 10.1021/jm100668r
BindingDB Entry DOI: 10.7270/Q2BR8SD7
More data for this
Ligand-Target Pair