new BindingDB logo
myBDB logout

BDBM50327866 (1-butylpiperidin-4-yl)methyl 8-amino-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1257991

SMILES: CCCCN1CCC(COC(=O)c2ccc(N)c3OCCOc23)CC1

InChI Key: InChIKey=LTSRVCVMUIEULO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327866   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 4 (5-HT4)


(Homo sapiens (Human))
BDBM50327866
PNG
((1-butylpiperidin-4-yl)methyl 8-amino-2,3-dihydrob...)
Show SMILES CCCCN1CCC(COC(=O)c2ccc(N)c3OCCOc23)CC1
Show InChI InChI=1S/C19H28N2O4/c1-2-3-8-21-9-6-14(7-10-21)13-25-19(22)15-4-5-16(20)18-17(15)23-11-12-24-18/h4-5,14H,2-3,6-13,20H2,1H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.40n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4 receptor expressed in HEK293 cells


J Med Chem 53: 7035-47 (2010)


Article DOI: 10.1021/jm100668r
BindingDB Entry DOI: 10.7270/Q2BR8SD7
More data for this
Ligand-Target Pair