BDBM50327896 2-amino-4-methyl-8-(1-methylethyl)-6-(1H-pyrazol-4-yl)pteridin-7(8H)-one::2-amino-8-isopropyl-4-methyl-6-(1H-pyrazol-4-yl)pteridin-7(8H)-one::CHEMBL1234917

SMILES: CC(C)n1c2nc(N)nc(C)c2nc(-c2cn[nH]c2)c1=O

InChI Key: InChIKey=YIFGKPFEGAUADP-UHFFFAOYSA-N

Data: 1 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50327896 (2-amino-4-methyl-8-(1-methylethyl)-6-(1H-pyrazol-4...) Show SMILES CC(C)n1c2nc(N)nc(C)c2nc(-c2cn[nH]c2)c1=O Show InChI InChI=1S/C13H15N7O/c1-6(2)20-11-9(7(3)17-13(14)19-11)18-10(12(20)21)8-4-15-16-5-8/h4-6H,1-3H3,(H,15,16)(H2,14,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 20: 6096-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.045 BindingDB Entry DOI: 10.7270/Q2ZK5GWH
					More data for this Ligand-Target Pair