BDBM50327900 2-amino-8-isopropyl-6-(6-methoxypyridin-3-yl)-4-methylpteridin-7(8H)-one::CHEMBL1258679

SMILES: COc1ccc(cn1)-c1nc2c(C)nc(N)nc2n(C(C)C)c1=O

InChI Key: InChIKey=QERFJHUBLDEEJL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50327900 (2-amino-8-isopropyl-6-(6-methoxypyridin-3-yl)-4-me...) Show SMILES COc1ccc(cn1)-c1nc2c(C)nc(N)nc2n(C(C)C)c1=O Show InChI InChI=1S/C16H18N6O2/c1-8(2)22-14-12(9(3)19-16(17)21-14)20-13(15(22)23)10-5-6-11(24-4)18-7-10/h5-8H,1-4H3,(H2,17,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 20: 6096-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.045 BindingDB Entry DOI: 10.7270/Q2ZK5GWH
					More data for this Ligand-Target Pair