BDBM50327913 3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-thieno[3,2-c]pyrazole-5-carboxylic acid phenylamide::CHEMBL1258460

SMILES: CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1[nH]nc2cc(sc12)C(=O)Nc1ccccc1

InChI Key: InChIKey=PAEFKBWKOFUIRD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50327913 (3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...) Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1[nH]nc2cc(sc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C24H24N6O2S/c1-29-11-13-30(14-12-29)18-9-7-16(8-10-18)23(31)26-22-21-19(27-28-22)15-20(33-21)24(32)25-17-5-3-2-4-6-17/h2-10,15H,11-14H2,1H3,(H,25,32)(H2,26,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences-Oncology Curated by ChEMBL					Assay Description Inhibition of AurA				Bioorg Med Chem 18: 7113-20 (2010) Article DOI: 10.1016/j.bmc.2010.07.048 BindingDB Entry DOI: 10.7270/Q2Q240GM
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