BDBM50328214 1,1,1,3,3,3-hexafluoro-2-(2-(4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)thiazol-5-yl)propan-2-ol::CHEMBL1258251
SMILES: CS(=O)(=O)c1cccc(c1)N1CCN(CC1)c1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F
InChI Key: InChIKey=WNJLSYBWYSVWSL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Malonyl-CoA decarboxylase (Homo sapiens (Human)) | BDBM50328214 (1,1,1,3,3,3-hexafluoro-2-(2-(4-(3-(methylsulfonyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human MCD | Bioorg Med Chem Lett 20: 6088-92 (2010) Article DOI: 10.1016/j.bmcl.2010.08.047 BindingDB Entry DOI: 10.7270/Q2542NTX | |||||||||||
More data for this Ligand-Target Pair |