BDBM50328214 1,1,1,3,3,3-hexafluoro-2-(2-(4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)thiazol-5-yl)propan-2-ol::CHEMBL1258251

SMILES: CS(=O)(=O)c1cccc(c1)N1CCN(CC1)c1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=WNJLSYBWYSVWSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malonyl-CoA decarboxylase (Homo sapiens (Human))	BDBM50328214 (1,1,1,3,3,3-hexafluoro-2-(2-(4-(3-(methylsulfonyl)...) Show SMILES CS(=O)(=O)c1cccc(c1)N1CCN(CC1)c1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H17F6N3O3S2/c1-31(28,29)12-4-2-3-11(9-12)25-5-7-26(8-6-25)14-24-10-13(30-14)15(27,16(18,19)20)17(21,22)23/h2-4,9-10,27H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MCD				Bioorg Med Chem Lett 20: 6088-92 (2010) Article DOI: 10.1016/j.bmcl.2010.08.047 BindingDB Entry DOI: 10.7270/Q2542NTX
					More data for this Ligand-Target Pair