BDBM50328232 1,1,1,3,3,3-hexafluoro-2-(2-(4-phenylpiperidin-1-yl)thiazol-5-yl)propan-2-ol::CHEMBL1257432

SMILES: OC(c1cnc(s1)N1CCC(CC1)c1ccccc1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=YLYHUUBCDDULBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malonyl-CoA decarboxylase (Homo sapiens (Human))	BDBM50328232 (1,1,1,3,3,3-hexafluoro-2-(2-(4-phenylpiperidin-1-y...) Show SMILES OC(c1cnc(s1)N1CCC(CC1)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H16F6N2OS/c18-16(19,20)15(26,17(21,22)23)13-10-24-14(27-13)25-8-6-12(7-9-25)11-4-2-1-3-5-11/h1-5,10,12,26H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MCD				Bioorg Med Chem Lett 20: 6088-92 (2010) Article DOI: 10.1016/j.bmcl.2010.08.047 BindingDB Entry DOI: 10.7270/Q2542NTX
					More data for this Ligand-Target Pair