BDBM50328273 7-fluoro-3-methyl-5-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine::CHEMBL1257670

SMILES: Cc1n[nH]c2Nc3ccc(F)cc3C(=Nc12)c1ccccc1

InChI Key: InChIKey=JSBYEJZZQCWTMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin E/G1/S-specific cyclin E2 (Homo sapiens (Human))	BDBM50328273 (7-fluoro-3-methyl-5-phenyl-2,10-dihydrobenzo[e]pyr...) Show SMILES Cc1n[nH]c2Nc3ccc(F)cc3C(=Nc12)c1ccccc1 |c:14| Show InChI InChI=1S/C17H13FN4/c1-10-15-17(22-21-10)19-14-8-7-12(18)9-13(14)16(20-15)11-5-3-2-4-6-11/h2-9H,1H3,(H2,19,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2-cyclin E				Bioorg Med Chem Lett 20: 5984-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.079 BindingDB Entry DOI: 10.7270/Q21C1X42
					More data for this Ligand-Target Pair