BDBM50328392 3-(azulen-1-ylmethylene)indolin-2-one::CHEMBL1257560

SMILES: O=C1Nc2ccccc2C1=Cc1ccc2cccccc12

InChI Key: InChIKey=JASLPUAXLBHAQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328392 (3-(azulen-1-ylmethylene)indolin-2-one | CHEMBL1257...) Show SMILES O=C1Nc2ccccc2C1=Cc1ccc2cccccc12 |w:10.12| Show InChI InChI=1S/C19H13NO/c21-19-17(16-8-4-5-9-18(16)20-19)12-14-11-10-13-6-2-1-3-7-15(13)14/h1-12H,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
					More data for this Ligand-Target Pair