BDBM50328393 (Z)-3-(azulen-1-ylmethylene)-5-fluoroindolin-2-one::CHEMBL1257561

SMILES: Fc1ccc2NC(=O)\C(=C/c3ccc4cccccc34)c2c1

InChI Key: InChIKey=GTINQHKPVMOROA-YVLHZVERSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328393 ((Z)-3-(azulen-1-ylmethylene)-5-fluoroindolin-2-one...) Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc4cccccc34)c2c1 Show InChI InChI=1S/C19H12FNO/c20-14-8-9-18-16(11-14)17(19(22)21-18)10-13-7-6-12-4-2-1-3-5-15(12)13/h1-11H,(H,21,22)/b17-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
					More data for this Ligand-Target Pair