BDBM50328395 (Z)-3-(azulen-1-ylmethylene)-5-bromoindolin-2-one::CHEMBL1257681
SMILES: Brc1ccc2NC(=O)\C(=C/c3ccc4cccccc34)c2c1
InChI Key: InChIKey=XOYQROSFUKTOQG-YVLHZVERSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50328395 ((Z)-3-(azulen-1-ylmethylene)-5-bromoindolin-2-one ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Technology Research Institute Curated by ChEMBL | Assay Description Inhibition of FLT3 by time resolved fluorescence method | Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51 | |||||||||||
More data for this Ligand-Target Pair |