BDBM50328409 (Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazulen-1-yl)methylene)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one::CHEMBL1258376

SMILES: CN(C)CCCOc1ccccc2c(\C=C3/C(=O)Nc4ncccc34)cc(C)c12

InChI Key: InChIKey=BOGKUOUVWUICFV-HKWRFOASSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328409 ((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...) Show SMILES CN(C)CCCOc1ccccc2c(\C=C3/C(=O)Nc4ncccc34)cc(C)c12 Show InChI InChI=1S/C24H25N3O2/c1-16-14-17(15-20-19-9-6-11-25-23(19)26-24(20)28)18-8-4-5-10-21(22(16)18)29-13-7-12-27(2)3/h4-6,8-11,14-15H,7,12-13H2,1-3H3,(H,25,26,28)/b20-15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
					More data for this Ligand-Target Pair