BDBM50328410 (Z)-5-fluoro-3-((3-methyl-4-(3-morpholinopropoxy)azulen-1-yl)methylene)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one::CHEMBL1258377

SMILES: Cc1cc(\C=C2/C(=O)Nc3ncc(F)cc23)c2ccccc(OCCCN3CCOCC3)c12

InChI Key: InChIKey=BUDGSBIZCIHODS-HMAPJEAMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328410 ((Z)-5-fluoro-3-((3-methyl-4-(3-morpholinopropoxy)a...) Show SMILES Cc1cc(\C=C2/C(=O)Nc3ncc(F)cc23)c2ccccc(OCCCN3CCOCC3)c12 Show InChI InChI=1S/C26H26FN3O3/c1-17-13-18(14-22-21-15-19(27)16-28-25(21)29-26(22)31)20-5-2-3-6-23(24(17)20)33-10-4-7-30-8-11-32-12-9-30/h2-3,5-6,13-16H,4,7-12H2,1H3,(H,28,29,31)/b22-14-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
					More data for this Ligand-Target Pair