BDBM50328417 (Z)-4,5-difluoro-3-((3-methyl-4-(3-morpholinopropoxy)azulen-1-yl)methylene)indolin-2-one::CHEMBL1258831

SMILES: Cc1cc(\C=C2/C(=O)Nc3ccc(F)c(F)c23)c2ccccc(OCCCN3CCOCC3)c12

InChI Key: InChIKey=GWRSJXLJZMPWFN-SILNSSARSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328417 ((Z)-4,5-difluoro-3-((3-methyl-4-(3-morpholinopropo...) Show SMILES Cc1cc(\C=C2/C(=O)Nc3ccc(F)c(F)c23)c2ccccc(OCCCN3CCOCC3)c12 Show InChI InChI=1S/C27H26F2N2O3/c1-17-15-18(16-20-25-22(30-27(20)32)8-7-21(28)26(25)29)19-5-2-3-6-23(24(17)19)34-12-4-9-31-10-13-33-14-11-31/h2-3,5-8,15-16H,4,9-14H2,1H3,(H,30,32)/b20-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
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