BDBM50328433 3-methyl-N-(4-morpholinophenyl)-6-(pyridin-3-yl)imidazo[1,2-a]pyrazin-8-amine::CHEMBL1258490

SMILES: Cc1cnc2c(Nc3ccc(cc3)N3CCOCC3)nc(cn12)-c1cccnc1

InChI Key: InChIKey=LBRCWQJHXCIDHV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50328433 (3-methyl-N-(4-morpholinophenyl)-6-(pyridin-3-yl)im...) Show SMILES Cc1cnc2c(Nc3ccc(cc3)N3CCOCC3)nc(cn12)-c1cccnc1 Show InChI InChI=1S/C22H22N6O/c1-16-13-24-22-21(26-20(15-28(16)22)17-3-2-8-23-14-17)25-18-4-6-19(7-5-18)27-9-11-29-12-10-27/h2-8,13-15H,9-12H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human aurora A				Bioorg Med Chem Lett 20: 5988-93 (2010) Article DOI: 10.1016/j.bmcl.2010.08.091 BindingDB Entry DOI: 10.7270/Q2H995D7
					More data for this Ligand-Target Pair