BDBM50328449 4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one::CHEMBL1258036

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cc2CCc3ccc(CCc1cc2)cc3

InChI Key: InChIKey=FMZYTGKVWBHUEI-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50328449 (4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cc2CCc3ccc(CCc1cc2)cc3 Show InChI InChI=1S/C30H33FN2O/c31-28-15-13-27(14-16-28)30(34)2-1-17-32-18-20-33(21-19-32)29-22-25-8-7-23-3-5-24(6-4-23)9-11-26(29)12-10-25/h3-6,10,12-16,22H,1-2,7-9,11,17-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 53: 7219-28 (2010) Article DOI: 10.1021/jm100899z BindingDB Entry DOI: 10.7270/Q27W6CDZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50328449 (4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cc2CCc3ccc(CCc1cc2)cc3 Show InChI InChI=1S/C30H33FN2O/c31-28-15-13-27(14-16-28)30(34)2-1-17-32-18-20-33(21-19-32)29-22-25-8-7-23-3-5-24(6-4-23)9-11-26(29)12-10-25/h3-6,10,12-16,22H,1-2,7-9,11,17-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells				J Med Chem 53: 7219-28 (2010) Article DOI: 10.1021/jm100899z BindingDB Entry DOI: 10.7270/Q27W6CDZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50328449 (4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cc2CCc3ccc(CCc1cc2)cc3 Show InChI InChI=1S/C30H33FN2O/c31-28-15-13-27(14-16-28)30(34)2-1-17-32-18-20-33(21-19-32)29-22-25-8-7-23-3-5-24(6-4-23)9-11-26(29)12-10-25/h3-6,10,12-16,22H,1-2,7-9,11,17-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells				J Med Chem 53: 7219-28 (2010) Article DOI: 10.1021/jm100899z BindingDB Entry DOI: 10.7270/Q27W6CDZ
					More data for this Ligand-Target Pair
5-HT2 (PIG)	BDBM50328449 (4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cc2CCc3ccc(CCc1cc2)cc3 Show InChI InChI=1S/C30H33FN2O/c31-28-15-13-27(14-16-28)30(34)2-1-17-32-18-20-33(21-19-32)29-22-25-8-7-23-3-5-24(6-4-23)9-11-26(29)12-10-25/h3-6,10,12-16,22H,1-2,7-9,11,17-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from 5-HT2 receptor in pig cortex membranes				J Med Chem 53: 7219-28 (2010) Article DOI: 10.1021/jm100899z BindingDB Entry DOI: 10.7270/Q27W6CDZ
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Sus scrofa)	BDBM50328449 (4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cc2CCc3ccc(CCc1cc2)cc3 Show InChI InChI=1S/C30H33FN2O/c31-28-15-13-27(14-16-28)30(34)2-1-17-32-18-20-33(21-19-32)29-22-25-8-7-23-3-5-24(6-4-23)9-11-26(29)12-10-25/h3-6,10,12-16,22H,1-2,7-9,11,17-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in pig striatal membranes				J Med Chem 53: 7219-28 (2010) Article DOI: 10.1021/jm100899z BindingDB Entry DOI: 10.7270/Q27W6CDZ
					More data for this Ligand-Target Pair