BDBM50328753 5-amino-4-hydroxy-3-((4-sulfonatophenyl)diazenyl)naphthalene-2,7-disulfonate::CHEMBL1269836
SMILES: Nc1cc(cc2cc(c(N=Nc3ccc(cc3)S(O)(=O)=O)c(O)c12)S(O)(=O)=O)S(O)(=O)=O
InChI Key: InChIKey=PXRHUEYMJGSGOS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-arginine N-methyltransferase 1 (Homo sapiens (Human)) | BDBM50328753 (5-amino-4-hydroxy-3-((4-sulfonatophenyl)diazenyl)n...) | PDB B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scint... | J Med Chem 53: 6028-39 (2010) Article DOI: 10.1021/jm100416n BindingDB Entry DOI: 10.7270/Q2251JDB | |||||||||||
More data for this Ligand-Target Pair |