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SMILES: Cc1ccc(Nc2cccc3cccc(c23)S(N)(=O)=O)cc1

InChI Key: InChIKey=QMOBQPKJHYAHQJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328754   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 1 [11-371]


(Homo sapiens (Human))		BDBM50328754
PNG
(8-(p-tolylamino)naphthalene-1-sulfonamide | CHEMBL...)
Show SMILES Cc1ccc(Nc2cccc3cccc(c23)S(N)(=O)=O)cc1
Show InChI InChI=1S/C17H16N2O2S/c1-12-8-10-14(11-9-12)19-15-6-2-4-13-5-3-7-16(17(13)15)22(18,20)21/h2-11,19H,1H3,(H2,18,20,21)
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.67E+5n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scint...

J Med Chem 53: 6028-39 (2010)


Article DOI: 10.1021/jm100416n
BindingDB Entry DOI: 10.7270/Q2251JDB
More data for this
Ligand-Target Pair