BDBM50328767 3-(4-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)phenyl)propanoic acid::CHEMBL1271168

SMILES: CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(n1)-c1ccc(CCC(O)=O)cc1

InChI Key: InChIKey=BGILUSFJZNBOJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50328767 (3-(4-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(n1)-c1ccc(CCC(O)=O)cc1 Show InChI InChI=1S/C27H28N4O3/c1-27(2,3)23-17-24(31(30-23)20-14-11-18(12-15-20)13-16-25(32)33)29-26(34)28-22-10-6-8-19-7-4-5-9-21(19)22/h4-12,14-15,17H,13,16H2,1-3H3,(H,32,33)(H2,28,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals LLC Curated by ChEMBL					Assay Description Inhibition of p38alpha by fluoroprobe binding assay				Bioorg Med Chem Lett 20: 5793-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.134 BindingDB Entry DOI: 10.7270/Q2XD11WK
					More data for this Ligand-Target Pair