BDBM50328768 1-(5-tert-Butyl-2-{4-[2-(1,1-dioxo-1lambda6-thiomorpholin-4-yl)-2-oxo-ethyl]-phenyl}-2H-pyrazol-3-yl)-3-(2,3-dichloro-phenyl)-urea::CHEMBL1271268

SMILES: CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(n1)-c1ccc(CC(=O)N2CCS(=O)(=O)CC2)cc1

InChI Key: InChIKey=TTXGXKCRIYRWKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50328768 (1-(5-tert-Butyl-2-{4-[2-(1,1-dioxo-1lambda6-thiomo...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(n1)-c1ccc(CC(=O)N2CCS(=O)(=O)CC2)cc1 Show InChI InChI=1S/C26H29Cl2N5O4S/c1-26(2,3)21-16-22(30-25(35)29-20-6-4-5-19(27)24(20)28)33(31-21)18-9-7-17(8-10-18)15-23(34)32-11-13-38(36,37)14-12-32/h4-10,16H,11-15H2,1-3H3,(H2,29,30,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals LLC Curated by ChEMBL					Assay Description Inhibition of p38alpha by fluoroprobe binding assay				Bioorg Med Chem Lett 20: 5793-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.134 BindingDB Entry DOI: 10.7270/Q2XD11WK
					More data for this Ligand-Target Pair