BDBM50328771 2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(2-fluorophenyl)-1H-pyrazol-1-yl)phenyl)acetamide::CHEMBL1269838

SMILES: NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1ccccc1F

InChI Key: InChIKey=COUYOVKEAITHBW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50328771 (2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(2-fluoro...) Show SMILES NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1ccccc1F Show InChI InChI=1S/C24H18Cl2FN5O2/c25-17-8-4-10-19(23(17)26)29-24(34)30-22-13-20(16-7-1-2-9-18(16)27)31-32(22)15-6-3-5-14(11-15)12-21(28)33/h1-11,13H,12H2,(H2,28,33)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals LLC Curated by ChEMBL					Assay Description Binding affinity to phosphorylated p38alpha by fluoroprobe binding assay				Bioorg Med Chem Lett 20: 5793-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.134 BindingDB Entry DOI: 10.7270/Q2XD11WK
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50328771 (2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(2-fluoro...) Show SMILES NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1ccccc1F Show InChI InChI=1S/C24H18Cl2FN5O2/c25-17-8-4-10-19(23(17)26)29-24(34)30-22-13-20(16-7-1-2-9-18(16)27)31-32(22)15-6-3-5-14(11-15)12-21(28)33/h1-11,13H,12H2,(H2,28,33)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals LLC Curated by ChEMBL					Assay Description Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assay				Bioorg Med Chem Lett 20: 5793-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.134 BindingDB Entry DOI: 10.7270/Q2XD11WK
					More data for this Ligand-Target Pair