BDBM50328773 2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen-3-yl)-1H-pyrazol-1-yl)phenyl)acetamide::CHEMBL1269946

SMILES: NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1ccsc1

InChI Key: InChIKey=FQLTVXWHQWGJRK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50328773 (2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...) Show SMILES NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1ccsc1 Show InChI InChI=1S/C22H17Cl2N5O2S/c23-16-5-2-6-17(21(16)24)26-22(31)27-20-11-18(14-7-8-32-12-14)28-29(20)15-4-1-3-13(9-15)10-19(25)30/h1-9,11-12H,10H2,(H2,25,30)(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals LLC Curated by ChEMBL					Assay Description Binding affinity to phosphorylated p38alpha by fluoroprobe binding assay				Bioorg Med Chem Lett 20: 5793-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.134 BindingDB Entry DOI: 10.7270/Q2XD11WK
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50328773 (2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...) Show SMILES NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1ccsc1 Show InChI InChI=1S/C22H17Cl2N5O2S/c23-16-5-2-6-17(21(16)24)26-22(31)27-20-11-18(14-7-8-32-12-14)28-29(20)15-4-1-3-13(9-15)10-19(25)30/h1-9,11-12H,10H2,(H2,25,30)(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals LLC Curated by ChEMBL					Assay Description Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assay				Bioorg Med Chem Lett 20: 5793-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.134 BindingDB Entry DOI: 10.7270/Q2XD11WK
					More data for this Ligand-Target Pair