BDBM50328801 1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-ol::CHEMBL1269843

SMILES: CC1CC(O)(C#Cc2cccc3ccccc23)C(C)CN1C

InChI Key: InChIKey=UATGXLFLKRXZBK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328801   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328801 (1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidi...) Show SMILES CC1CC(O)(C#Cc2cccc3ccccc23)C(C)CN1C Show InChI InChI=1S/C20H23NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,13-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Athersys Inc. Curated by ChEMBL					Assay Description Antagonist activity against human histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...				Bioorg Med Chem Lett 20: 6246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.099 BindingDB Entry DOI: 10.7270/Q2DF6RGG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mus musculus)	BDBM50328801 (1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidi...) Show SMILES CC1CC(O)(C#Cc2cccc3ccccc23)C(C)CN1C Show InChI InChI=1S/C20H23NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,13-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Athersys Inc. Curated by ChEMBL					Assay Description Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...				Bioorg Med Chem Lett 20: 6246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.099 BindingDB Entry DOI: 10.7270/Q2DF6RGG
					More data for this Ligand-Target Pair