BDBM50328810 CHEMBL1270166::rac-6-methyl-7-(naphthalen-1-ylethynyl)octahydroindolizin-7-ol

SMILES: CC1CN2CCCC2CC1(O)C#Cc1cccc2ccccc12

InChI Key: InChIKey=KJULEEZSUWCDAJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328810 (CHEMBL1270166 | rac-6-methyl-7-(naphthalen-1-yleth...) Show SMILES CC1CN2CCCC2CC1(O)C#Cc1cccc2ccccc12 Show InChI InChI=1S/C21H23NO/c1-16-15-22-13-5-9-19(22)14-21(16,23)12-11-18-8-4-7-17-6-2-3-10-20(17)18/h2-4,6-8,10,16,19,23H,5,9,13-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Athersys Inc. Curated by ChEMBL					Assay Description Antagonist activity against human histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...				Bioorg Med Chem Lett 20: 6246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.099 BindingDB Entry DOI: 10.7270/Q2DF6RGG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mus musculus)	BDBM50328810 (CHEMBL1270166 | rac-6-methyl-7-(naphthalen-1-yleth...) Show SMILES CC1CN2CCCC2CC1(O)C#Cc1cccc2ccccc12 Show InChI InChI=1S/C21H23NO/c1-16-15-22-13-5-9-19(22)14-21(16,23)12-11-18-8-4-7-17-6-2-3-10-20(17)18/h2-4,6-8,10,16,19,23H,5,9,13-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Athersys Inc. Curated by ChEMBL					Assay Description Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...				Bioorg Med Chem Lett 20: 6246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.099 BindingDB Entry DOI: 10.7270/Q2DF6RGG
					More data for this Ligand-Target Pair