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BDBM50328940 (4-isopropyl-1,4-diazepan-1-yl)(1-methyl-3-(morpholinomethyl)-1H-indol-6-yl)methanone::CHEMBL1271381

SMILES: CC(C)N1CCCN(CC1)C(=O)c1ccc2c(CN3CCOCC3)cn(C)c2c1

InChI Key: InChIKey=PWJXWSKGZAZFAG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328940   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50328940
PNG
((4-isopropyl-1,4-diazepan-1-yl)(1-methyl-3-(morpho...)
Show SMILES CC(C)N1CCCN(CC1)C(=O)c1ccc2c(CN3CCOCC3)cn(C)c2c1
Show InChI InChI=1S/C23H34N4O2/c1-18(2)26-7-4-8-27(10-9-26)23(28)19-5-6-21-20(16-24(3)22(21)15-19)17-25-11-13-29-14-12-25/h5-6,15-16,18H,4,7-14,17H2,1-3H3
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Similars
Article
PubMed
 0.900n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...

Bioorg Med Chem Lett 20: 6226-30 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.103
BindingDB Entry DOI: 10.7270/Q2CF9QB3
More data for this
Ligand-Target Pair