BDBM50328962 CHEMBL1270563::N-{5-[(5-Aminopentyl)(methyl)amino]pentyl}-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

SMILES: CN(CCCCCN)CCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=ZWEUSOIZQIEIES-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50328962 (CHEMBL1270563 | N-{5-[(5-Aminopentyl)(methyl)amino...) Show SMILES CN(CCCCCN)CCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H36Cl3N5O/c1-20-26(28(37)33-16-6-4-8-18-35(2)17-7-3-5-15-32)34-36(25-14-13-23(30)19-24(25)31)27(20)21-9-11-22(29)12-10-21/h9-14,19H,3-8,15-18,32H2,1-2H3,(H,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]SR141716 from human CB1 receptor expressed in HEK293 cells				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50328962 (CHEMBL1270563 | N-{5-[(5-Aminopentyl)(methyl)amino...) Show SMILES CN(CCCCCN)CCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H36Cl3N5O/c1-20-26(28(37)33-16-6-4-8-18-35(2)17-7-3-5-15-32)34-36(25-14-13-23(30)19-24(25)31)27(20)21-9-11-22(29)12-10-21/h9-14,19H,3-8,15-18,32H2,1-2H3,(H,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50328962 (CHEMBL1270563 | N-{5-[(5-Aminopentyl)(methyl)amino...) Show SMILES CN(CCCCCN)CCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H36Cl3N5O/c1-20-26(28(37)33-16-6-4-8-18-35(2)17-7-3-5-15-32)34-36(25-14-13-23(30)19-24(25)31)27(20)21-9-11-22(29)12-10-21/h9-14,19H,3-8,15-18,32H2,1-2H3,(H,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in CHOK1 cells				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50328962 (CHEMBL1270563 | N-{5-[(5-Aminopentyl)(methyl)amino...) Show SMILES CN(CCCCCN)CCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H36Cl3N5O/c1-20-26(28(37)33-16-6-4-8-18-35(2)17-7-3-5-15-32)34-36(25-14-13-23(30)19-24(25)31)27(20)21-9-11-22(29)12-10-21/h9-14,19H,3-8,15-18,32H2,1-2H3,(H,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.04E+3	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at rat brain CB1 receptor assessed as inhibition of [35S]GTPgammaS binding				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair