BDBM50328964 CHEMBL1269771::N,N'-[(Methylimino)dinonane-9,1-diyl]bis[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide]

SMILES: CN(CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=IUMPBUYJPRNFHP-UHFFFAOYSA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50328964 (CHEMBL1269771 | N,N'-[(Methylimino)dinonane-9,1-di...) Show SMILES CN(CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C53H61Cl6N7O2/c1-36-48(62-65(46-28-26-42(56)34-44(46)58)50(36)38-18-22-40(54)23-19-38)52(67)60-30-14-10-6-4-8-12-16-32-64(3)33-17-13-9-5-7-11-15-31-61-53(68)49-37(2)51(39-20-24-41(55)25-21-39)66(63-49)47-29-27-43(57)35-45(47)59/h18-29,34-35H,4-17,30-33H2,1-3H3,(H,60,67)(H,61,68)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	94.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]SR141716 from human CB1 receptor expressed in HEK293 cells				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50328964 (CHEMBL1269771 | N,N'-[(Methylimino)dinonane-9,1-di...) Show SMILES CN(CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C53H61Cl6N7O2/c1-36-48(62-65(46-28-26-42(56)34-44(46)58)50(36)38-18-22-40(54)23-19-38)52(67)60-30-14-10-6-4-8-12-16-32-64(3)33-17-13-9-5-7-11-15-31-61-53(68)49-37(2)51(39-20-24-41(55)25-21-39)66(63-49)47-29-27-43(57)35-45(47)59/h18-29,34-35H,4-17,30-33H2,1-3H3,(H,60,67)(H,61,68)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	247	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50328964 (CHEMBL1269771 | N,N'-[(Methylimino)dinonane-9,1-di...) Show SMILES CN(CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C53H61Cl6N7O2/c1-36-48(62-65(46-28-26-42(56)34-44(46)58)50(36)38-18-22-40(54)23-19-38)52(67)60-30-14-10-6-4-8-12-16-32-64(3)33-17-13-9-5-7-11-15-31-61-53(68)49-37(2)51(39-20-24-41(55)25-21-39)66(63-49)47-29-27-43(57)35-45(47)59/h18-29,34-35H,4-17,30-33H2,1-3H3,(H,60,67)(H,61,68)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in CHOK1 cells				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50328964 (CHEMBL1269771 | N,N'-[(Methylimino)dinonane-9,1-di...) Show SMILES CN(CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C53H61Cl6N7O2/c1-36-48(62-65(46-28-26-42(56)34-44(46)58)50(36)38-18-22-40(54)23-19-38)52(67)60-30-14-10-6-4-8-12-16-32-64(3)33-17-13-9-5-7-11-15-31-61-53(68)49-37(2)51(39-20-24-41(55)25-21-39)66(63-49)47-29-27-43(57)35-45(47)59/h18-29,34-35H,4-17,30-33H2,1-3H3,(H,60,67)(H,61,68)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	161	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at human brain CB1 receptor assessed as inhibition for [35S]GTPgammaS binding				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50328964 (CHEMBL1269771 | N,N'-[(Methylimino)dinonane-9,1-di...) Show SMILES CN(CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)CCCCCCCCCNC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C53H61Cl6N7O2/c1-36-48(62-65(46-28-26-42(56)34-44(46)58)50(36)38-18-22-40(54)23-19-38)52(67)60-30-14-10-6-4-8-12-16-32-64(3)33-17-13-9-5-7-11-15-31-61-53(68)49-37(2)51(39-20-24-41(55)25-21-39)66(63-49)47-29-27-43(57)35-45(47)59/h18-29,34-35H,4-17,30-33H2,1-3H3,(H,60,67)(H,61,68)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at rat brain CB1 receptor assessed as inhibition of [35S]GTPgammaS binding				J Med Chem 53: 7048-60 (2010) Article DOI: 10.1021/jm1006676 BindingDB Entry DOI: 10.7270/Q27P8ZMC
					More data for this Ligand-Target Pair