null

SMILES: CS(=O)(=O)c1cccc(Nc2nccc(n2)N(CCO)c2c3OCOc3ccc2Cl)c1

InChI Key: InChIKey=VWLBBUUEBWHUIC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329064 (2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methyl...) Show SMILES CS(=O)(=O)c1cccc(Nc2nccc(n2)N(CCO)c2c3OCOc3ccc2Cl)c1 Show InChI InChI=1S/C20H19ClN4O5S/c1-31(27,28)14-4-2-3-13(11-14)23-20-22-8-7-17(24-20)25(9-10-26)18-15(21)5-6-16-19(18)30-12-29-16/h2-8,11,26H,9-10,12H2,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329064 (2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methyl...) Show SMILES CS(=O)(=O)c1cccc(Nc2nccc(n2)N(CCO)c2c3OCOc3ccc2Cl)c1 Show InChI InChI=1S/C20H19ClN4O5S/c1-31(27,28)14-4-2-3-13(11-14)23-20-22-8-7-17(24-20)25(9-10-26)18-15(21)5-6-16-19(18)30-12-29-16/h2-8,11,26H,9-10,12H2,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair