BDBM50329086 (Z)-methyl 2-(6-nitro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate::CHEMBL1269409

SMILES: COC(=O)Cc1nc2cc(ccc2oc1=O)[N+]([O-])=O

InChI Key: InChIKey=LMPDTBPOJXDHEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,4-Dihydroxy-2-naphthoyl-CoA synthase (Mycobacterium tuberculosis)	BDBM50329086 ((Z)-methyl 2-(6-nitro-2-oxo-2H-benzo[b][1,4]oxazin...) Show SMILES COC(=O)Cc1nc2cc(ccc2oc1=O)[N+]([O-])=O Show InChI InChI=1S/C11H8N2O6/c1-18-10(14)5-8-11(15)19-9-3-2-6(13(16)17)4-7(9)12-8/h2-4H,5H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysis				Bioorg Med Chem Lett 20: 6306-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.076 BindingDB Entry DOI: 10.7270/Q2M045PR
					More data for this Ligand-Target Pair