BDBM50329088 (Z)-methyl 2-(7-methyl-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate::CHEMBL1269410

SMILES: COC(=O)Cc1nc2ccc(C)cc2oc1=O

InChI Key: InChIKey=JTJOHXRBKVUVMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,4-Dihydroxy-2-naphthoyl-CoA synthase (Mycobacterium tuberculosis)	BDBM50329088 ((Z)-methyl 2-(7-methyl-2-oxo-2H-benzo[b][1,4]oxazi...) Show SMILES COC(=O)Cc1nc2ccc(C)cc2oc1=O Show InChI InChI=1S/C12H11NO4/c1-7-3-4-8-10(5-7)17-12(15)9(13-8)6-11(14)16-2/h3-5H,6H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysis				Bioorg Med Chem Lett 20: 6306-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.076 BindingDB Entry DOI: 10.7270/Q2M045PR
					More data for this Ligand-Target Pair