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BDBM50329133 1,1,1-trifluoro-N-((1-(1-(pyridin-2-ylsulfonyl)-1H-indol-2-ylsulfonyl)piperidin-4-yl)methyl)methanesulfonamide::CHEMBL1270784

SMILES: FC(F)(F)S(=O)(=O)NCC1CCN(CC1)S(=O)(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccn1

InChI Key: InChIKey=JHALBSDIEUJFLE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329133   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50329133
PNG
(1,1,1-trifluoro-N-((1-(1-(pyridin-2-ylsulfonyl)-1H...)
Show SMILES FC(F)(F)S(=O)(=O)NCC1CCN(CC1)S(=O)(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C20H21F3N4O6S3/c21-20(22,23)36(32,33)25-14-15-8-11-26(12-9-15)35(30,31)19-13-16-5-1-2-6-17(16)27(19)34(28,29)18-7-3-4-10-24-18/h1-7,10,13,15,25H,8-9,11-12,14H2
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PC cid
PC sid
UniChem
Article
PubMed
0.900n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptor


Bioorg Med Chem Lett 20: 6785-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.126
BindingDB Entry DOI: 10.7270/Q26Q1XGJ
More data for this
Ligand-Target Pair