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BDBM50329156 (R)-1,1,1-trifluoro-N-(1-(4-(2-(2-fluorophenylsulfonyl)furan-3-ylsulfonyl)phenyl)ethyl)methanesulfonamide::CHEMBL1270480

SMILES: C[C@@H](NS(=O)(=O)C(F)(F)F)c1ccc(cc1)S(=O)(=O)c1ccoc1S(=O)(=O)c1ccccc1F

InChI Key: InChIKey=CHWADRKNMBPGOR-GFCCVEGCSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329156   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50329156
PNG
((R)-1,1,1-trifluoro-N-(1-(4-(2-(2-fluorophenylsulf...)
Show SMILES C[C@@H](NS(=O)(=O)C(F)(F)F)c1ccc(cc1)S(=O)(=O)c1ccoc1S(=O)(=O)c1ccccc1F |r|
Show InChI InChI=1S/C19H15F4NO7S3/c1-12(24-34(29,30)19(21,22)23)13-6-8-14(9-7-13)32(25,26)17-10-11-31-18(17)33(27,28)16-5-3-2-4-15(16)20/h2-12,24H,1H3/t12-/m1/s1
PDB

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PC cid
PC sid
UniChem
Article
PubMed
4.40n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptor


Bioorg Med Chem Lett 20: 6785-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.126
BindingDB Entry DOI: 10.7270/Q26Q1XGJ
More data for this
Ligand-Target Pair