BDBM50329173 CHEMBL1270391::N-((R)-1-(3,5-difluorophenyl)ethyl)-N-(((S)-2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-3-yl)methyl)pivalamide

SMILES: C[C@@H](N(Cc1cnc2cc3C[C@]4(Cc3cc2c1)C(=O)Nc1ncccc41)C(=O)C(C)(C)C)c1cc(F)cc(F)c1

InChI Key: InChIKey=RGMJGGSGBPLMKC-CVCYQNGTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50329173 (CHEMBL1270391 | N-((R)-1-(3,5-difluorophenyl)ethyl...) Show SMILES C[C@@H](N(Cc1cnc2cc3C[C@]4(Cc3cc2c1)C(=O)Nc1ncccc41)C(=O)C(C)(C)C)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C32H30F2N4O2/c1-18(20-10-24(33)13-25(34)11-20)38(30(40)31(2,3)4)17-19-8-21-9-22-14-32(15-23(22)12-27(21)36-16-19)26-6-5-7-35-28(26)37-29(32)39/h5-13,16,18H,14-15,17H2,1-4H3,(H,35,37,39)/t18-,32+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cells				Bioorg Med Chem Lett 20: 6827-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.105 BindingDB Entry DOI: 10.7270/Q2Z89CNJ
					More data for this Ligand-Target Pair