BDBM50329200 3-((3,3-dimethylmorpholino)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine::CHEMBL1270897

SMILES: Cc1cn2c(cnc2c(Nc2cc(CN3CCOCC3(C)C)ns2)n1)-c1cn[nH]c1

InChI Key: InChIKey=SGRYPBLWIZFTHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50329200 (3-((3,3-dimethylmorpholino)methyl)-N-(6-methyl-3-(...) Show SMILES Cc1cn2c(cnc2c(Nc2cc(CN3CCOCC3(C)C)ns2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C20H24N8OS/c1-13-10-28-16(14-7-22-23-8-14)9-21-19(28)18(24-13)25-17-6-15(26-30-17)11-27-4-5-29-12-20(27,2)3/h6-10H,4-5,11-12H2,1-3H3,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of LCK				Bioorg Med Chem Lett 20: 6739-43 (2010) Article DOI: 10.1016/j.bmcl.2010.08.140 BindingDB Entry DOI: 10.7270/Q2K074HX
					More data for this Ligand-Target Pair