BDBM50329429 5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-3-yl)-1Hpyrrole-3-carboxamide::CHEMBL1270619::US9670191, G13

SMILES: Cn1cc(-c2[nH]c(cc2C(N)=O)-c2ccnc(N)n2)c2ccccc12

InChI Key: InChIKey=NYNANQKQYVAHFV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM50329429 (5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-3-...) Show SMILES Cn1cc(-c2[nH]c(cc2C(N)=O)-c2ccnc(N)n2)c2ccccc12 Show InChI InChI=1S/C18H16N6O/c1-24-9-12(10-4-2-3-5-15(10)24)16-11(17(19)25)8-14(22-16)13-6-7-21-18(20)23-13/h2-9,22H,1H3,(H2,19,25)(H2,20,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...				US Patent US9670191 (2017) BindingDB Entry DOI: 10.7270/Q2X63K3K
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329429 (5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-3-...) Show SMILES Cn1cc(-c2[nH]c(cc2C(N)=O)-c2ccnc(N)n2)c2ccccc12 Show InChI InChI=1S/C18H16N6O/c1-24-9-12(10-4-2-3-5-15(10)24)16-11(17(19)25)8-14(22-16)13-6-7-21-18(20)23-13/h2-9,22H,1H3,(H2,19,25)(H2,20,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair