BDBM50329470 2-(3-Bromo-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-carboxamide::CHEMBL1270123::US9670191, A5

SMILES: NC(=O)c1cc([nH]c1-c1cccc(Br)c1)-c1ccncc1

InChI Key: InChIKey=VCHRCLNIIWLDLA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM50329470 (2-(3-Bromo-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...) Show SMILES NC(=O)c1cc([nH]c1-c1cccc(Br)c1)-c1ccncc1 Show InChI InChI=1S/C16H12BrN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...				US Patent US9670191 (2017) BindingDB Entry DOI: 10.7270/Q2X63K3K
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329470 (2-(3-Bromo-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...) Show SMILES NC(=O)c1cc([nH]c1-c1cccc(Br)c1)-c1ccncc1 Show InChI InChI=1S/C16H12BrN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair