BDBM50329629 CHEMBL1269786::ethyl 6-iodo-9H-pyrido[3,4-b]indole-3-carboxylate
SMILES: CCOC(=O)c1cc2c(cn1)[nH]c1ccc(I)cc21
InChI Key: InChIKey=LTYUPBZLKIUGQX-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50329629 (CHEMBL1269786 | ethyl 6-iodo-9H-pyrido[3,4-b]indol...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha1beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting | Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50329629 (CHEMBL1269786 | ethyl 6-iodo-9H-pyrido[3,4-b]indol...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha2beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting | Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50329629 (CHEMBL1269786 | ethyl 6-iodo-9H-pyrido[3,4-b]indol...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha3beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting | Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50329629 (CHEMBL1269786 | ethyl 6-iodo-9H-pyrido[3,4-b]indol...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 286 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha5beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting | Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA receptor alpha-4/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50329629 (CHEMBL1269786 | ethyl 6-iodo-9H-pyrido[3,4-b]indol...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha4beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting | Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA receptor alpha-6/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50329629 (CHEMBL1269786 | ethyl 6-iodo-9H-pyrido[3,4-b]indol...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha6beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting | Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B | |||||||||||
More data for this Ligand-Target Pair |