Found 3 hits for monomerid = 50329722 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50329722
(CHEMBL1271519 | endo-N-((1R,5R)-9-methyl-9-azabicy...)Show SMILES CN1[C@@H]2CCC[C@@H]1CC(C2)NC(=O)c1cccc2oc(nc12)N1CCOCC1 |r,TLB:0:1:3.4.5:7.8.9| Show InChI InChI=1S/C21H28N4O3/c1-24-15-4-2-5-16(24)13-14(12-15)22-20(26)17-6-3-7-18-19(17)23-21(28-18)25-8-10-27-11-9-25/h3,6-7,14-16H,2,4-5,8-13H2,1H3,(H,22,26)/t15-,16-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI
Curated by ChEMBL
| Assay Description Binding affinity to human HT3A receptor |
Bioorg Med Chem Lett 20: 6538-41 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.038 BindingDB Entry DOI: 10.7270/Q2Z31ZVH |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50329722
(CHEMBL1271519 | endo-N-((1R,5R)-9-methyl-9-azabicy...)Show SMILES CN1[C@@H]2CCC[C@@H]1CC(C2)NC(=O)c1cccc2oc(nc12)N1CCOCC1 |r,TLB:0:1:3.4.5:7.8.9| Show InChI InChI=1S/C21H28N4O3/c1-24-15-4-2-5-16(24)13-14(12-15)22-20(26)17-6-3-7-18-19(17)23-21(28-18)25-8-10-27-11-9-25/h3,6-7,14-16H,2,4-5,8-13H2,1H3,(H,22,26)/t15-,16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI
Curated by ChEMBL
| Assay Description Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 20: 6538-41 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.038 BindingDB Entry DOI: 10.7270/Q2Z31ZVH |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50329722
(CHEMBL1271519 | endo-N-((1R,5R)-9-methyl-9-azabicy...)Show SMILES CN1[C@@H]2CCC[C@@H]1CC(C2)NC(=O)c1cccc2oc(nc12)N1CCOCC1 |r,TLB:0:1:3.4.5:7.8.9| Show InChI InChI=1S/C21H28N4O3/c1-24-15-4-2-5-16(24)13-14(12-15)22-20(26)17-6-3-7-18-19(17)23-21(28-18)25-8-10-27-11-9-25/h3,6-7,14-16H,2,4-5,8-13H2,1H3,(H,22,26)/t15-,16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI
Curated by ChEMBL
| Assay Description Inhibition of human ERG expressed in HEK cells by patch clamp technique |
Bioorg Med Chem Lett 20: 6538-41 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.038 BindingDB Entry DOI: 10.7270/Q2Z31ZVH |
More data for this Ligand-Target Pair | |