null

SMILES: CC(C)N(C)c1nc2c(cccc2o1)C(=O)N[C@@H]1CN2CCC1CC2

InChI Key: InChIKey=PBZNWDCSSPCDNF-OAHLLOKOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50329755 (2-(1-(methylamino)ethyl)-N-((S)-quinuclidin-3-yl)b...) Show SMILES CC(C)N(C)c1nc2c(cccc2o1)C(=O)N[C@@H]1CN2CCC1CC2 |r,wD:17.18,TLB:16:17:21.20:23.24,(13.98,-18.53,;12.44,-18.54,;11.66,-17.21,;11.67,-19.87,;12.44,-21.21,;10.13,-19.88,;9.22,-18.62,;7.75,-19.1,;6.41,-18.34,;5.08,-19.11,;5.08,-20.65,;6.42,-21.43,;7.75,-20.65,;9.22,-21.13,;6.41,-16.8,;5.07,-16.03,;7.74,-16.03,;7.73,-14.49,;7.54,-13.11,;9.01,-12.46,;10.36,-13.07,;10.64,-14.47,;9.27,-13.83,;9.52,-11.93,;9.08,-10.82,)| Show InChI InChI=1S/C19H26N4O2/c1-12(2)22(3)19-21-17-14(5-4-6-16(17)25-19)18(24)20-15-11-23-9-7-13(15)8-10-23/h4-6,12-13,15H,7-11H2,1-3H3,(H,20,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human HT3A receptor				Bioorg Med Chem Lett 20: 6538-41 (2010) Article DOI: 10.1016/j.bmcl.2010.09.038 BindingDB Entry DOI: 10.7270/Q2Z31ZVH
					More data for this Ligand-Target Pair